Papers

Mizolastine is an antihistamine drug. Two simple, sensitive and accurate spectrophotometric methods have been developed for the determination of Mizolastine in pure state and in its pharmaceutical formulations. The developed Method A is based on the reaction between drug and 1, 10-phenanthroline with ferric chloride and ortho phosphoric acid to form a colored chromogen and it shows maximum absorption at l _max 510 nm and Linearity in the range of 100-500 µg/mL. Method B is based on oxidation of the drug in the presence of ferric chloride followed by complex formation with bathophenanthroline. The developed chromogen in Method B shows maximum absorption at l _max 615 nm; Linearity in the range of 50-250 µg/mL. The results obtained were statistically evaluated and were found to be accurate and reproducible.
 

The present study attempts to capture the environmental impacts of industrial effluent irrigation from a tanning industrial cluster. In the recent years, groundwater in the study area forms the mainstay of domestic water supply source for meeting the community needs. But the threat of chromium contamination in the ground waters is looming large over the study area. In view of this, it is of paramount importance to look for and to evaluate the chromium levels in the drinking waters of the area and assess their status of potability in the light of the criteria laid by Bureau of Indian standards (B.I.S) Chromate poisoning causes severe skin disorders such as allergic dermatitis and liver and kidney damage. There is considerable evidence that chromium is carcinogenic. Forty ground water samples were identified for sampling and chromium analysis, from the area covering about 1.2 Sq.Km, in and around the industrial cluster. The analysis reveals that 57.5% of the samples are non-potable due to the presence of excess chromium and the results show that there is a definite correlation between the ill health faced by the residents of the area and ground water contamination.
 

Radiation effect on mixed convection along a vertical plate with uniform surface temperature was studied by Hossain, M. A. and Takhar, H. S.¹. Soundalgekar, V. M. and Takhar, H. S. considered semi-infinite vertical plate and studied the Radiation effects on free convection flow². Similar problems were also studied by other researchers³,¹². Our aim is to study radiation effects on impulsively started infinite vertical porous plate in the presence of variable temperature. The temperature of plate is made to rise linearly with time. The fluid of our flow model is considered as gray, absorbing-emitting radiation but non- scattering medium.
 

In the present study, we investigate the relationship between Coronal Mass Ejection (CME) and Cosmic ray intensity (CRI) variation on long-term basis. In this work, we extend the effects of CMEs rates on cosmic rays for the solar cycle 23. To carry out the study, we take all Coronal Mass Ejection data of LASCO during the period of solar cycle 23. From the analysis, we observed a good relationship between occurrence rate of CMEs and cosmic ray intensity variation.

Ultrasonic velocity, density and viscosity have been measured for substituted heterocyclic drugs Silymarin, Rifampicin in 1, 4 dioxane at 303 k.. The measurement have been perform to evaluate acoustical parameter such as adiabatic compressibility (bs), Partial molal volume (f_v), intermolecular free length (L_f), apparent molal compressibility (f_k), specific acoustic impedance (Z), relative association (RA), salvation number(Sn), limiting apparent molal compressibility (f⁰_k), limiting apparent molal volume(f⁰_v) and their constant (S_k,S_v). The viscosity coefficient (A,B) evaluate by using johndole equation. These parameter throw the light on the solute-solvent interaction and solute-solute interaction.
 

Theoretical investigation has been carried out to evaluate the effect of plasma medium on the radiation characteristics of pentagonal microstrip antenna. The pentagonal microstrip antenna has been mapped on to circular patch. For this purpose the vector potential and scalar potential have been utilized to get the impressions for the electric field and magnetic field. The collision frequency has also been taken into account. It is observed that there is significant change in the radiation characteristics of pentagonal microstrip antenna. The radiation becomes more omini directional in half space with decreasing value of plasma frequency.

Phase behavior and structures of one-phase microemulsions of Triton X -100+1-penanol (1:5 molar ratios)/ cyclohexane/ brine have been studied by a combination of techniques such as crossed polaroid microscope, conductivity, viscosity and quasi-elastic light scattering (QELS). Two distinct isotropic one-phase microemulsion regions have been observed in the pseudo-ternary phase diagram. One isotropic single-phase microemulsion region exists in the water corner and the other one appears in the upper portion of the phase diagram which touches oil and surfactant vertexes. Electrical conductivities, viscosity and QELS measurements have been performed to locate the sub-regions in the single-phase microemulsion region. These measurements reveal that structural changes from water-in-oil microemulsion via bicontinuous structure to an oil-in-water microemulsion occurs with increase in weight fraction of water, f_w. The sizes of the microemulsion droplets was determined by QELS and were found in the range of 14-31 nm in the middle of the phase diagram. In the upper portion (at f_s> 60) of the phase diagram, the structure of microemulsion droplets is unclear.
 

Inclusion of effects of disturbances behind the shock waves moving in uniform and non-uniform medium modifies the approximate method used to investigate their propagation. The numerical estimates of the flow variable have been computed at the permissible shock front locations. The result has been presented through graphs and compared with the earlier results also²³.

Water is the most important natural resource which forms the core of the ecological system. The advent of remote sensing has opened up new vistas in groundwater prospects evaluation. The study area is part of Raisen district which is part of Betwa river sub- basin. The groundwater prospects evaluation in Raisen has been attempted based on mapping of the area constituting geology, lineament, geomorphology using IRS-1C LISS III and LANDSAT data. The integrated hydrogeomorphological map of the study area reveals that groundwater potential in delineated landforms such as infilled valleys and lineaments come under good to very good, shallow buried pediplaines and denudational hill come under moderate and structural hills, linear ridges and escarpments are under poor category. The present study shows that integration of all attributes provide more accurate result in groundwater potential zones identification.

There are no experimental reports on anti-inflammatory activities of Eichornia crassipes in literature. In this article, we report for the first time, the efficiency of Eichornia crassipes extract in the treatment against inflammation. The methanolic extract of Eichornia crassipes leaves were investigated for the evaluation of their anti-inflammatory potential on carrageenan-induced paw oedema in Wister rats. Leaf extract of Eichornia crassipes in dose 200mg/kg (P < 0.05) and 500mg/kg (P < 0.01) on orally administration gave significant reduction of rat paw oedema at all assessment times. The Eichornia crassipes leaf extract showed maximum inhibition of 52.54% at the dose of 500mg/kg after 4 hrs. Where as the standard drug showed 62.38% of inhibition. These observations revealed that Eichornia crassipes has significant anti-inflammatory property.