Experiments were conducted to determine the residues of 18 pesticides in water samples collected from Four Lakes (Kamana, Karanji, Kukkarahally and Dalvoi lakes) located in Mysore city and comparison of their contamination level with other agricultural water samples around Mysore district, Karnataka, India. These Samples were analyzed by Gas Chromatography (GC) consisting of Electron Capture Detector (ECD) to determination of organochlorine pesticides (OCPs) and Flame Photometric Detector (FPD) for the determination of organophosphorus pesticides (OPPs). All the lake water samples, as well as ground water samples, had no detectable pesticide residues. Instead, four pesticides including Aldrin, b-HCH, g-HCH, and 4,4-DDT were detected in other agricultural water samples. For the pesticides detected the presence of b-HCH and 4,4-DDT was comparatively more. All detected pesticides in water samples were in low concentrations except for b-HCH in one sample. No organophosphorus and atrazin pesticide residues were detected in water samples.