Substituted thieno[2,3-d]pyrimidin-4-yl-amines for evaluation of Anti-oxidant Activity
1 Nargund college of Pharmacy, BSK 3rd stage, Bangalore-560085 (India)
2 Dayananda Sagar College of Pharmacy, Shivage Hill, Kumarswamy Layout, Bangalore-560081 (India)
A series of novel 4-substituted-thieno[2,3-d]-pyrimidin-4-ylamines have been synthesized and tested for anti-oxidant activity. The synthesized 11 compounds all have shown anti-oxidant activity that differs in potency. The compounds were subjected to three methods to analyze their anti-oxidant potential a) DPPH (2,2-diphenyl-1-picrylhydrazyl) scavenging method, a) Hydrogen peroxide scavenging method and c) Nitric oxide radical scavenging method. Among the test compounds SLNA2, SLNA3 SLNA4, SLNA7 and SLNA9 have good potential as anti-oxidants.
Copy the following to cite this article:
SHACHINDRA L. NARGUND1, V. MURUGAN2, H J HRISHEKESHAVAN1 and L.V. G.NARGUND1, "Substituted thieno[2,3-d]pyrimidin-4-yl-amines for evaluation of Anti-oxidant Activity", Journal of Ultra Scientist of Physical Sciences, Volume 28, Issue 1, Page Number , 2016Copy the following to cite this URL:
SHACHINDRA L. NARGUND1, V. MURUGAN2, H J HRISHEKESHAVAN1 and L.V. G.NARGUND1, "Substituted thieno[2,3-d]pyrimidin-4-yl-amines for evaluation of Anti-oxidant Activity", Journal of Ultra Scientist of Physical Sciences, Volume 28, Issue 1, Page Number , 2016Available from: http://www.ultraphysicalsciences.org/paper/23/
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