We have considered the MHD flow of an incompressible fluid with heat and mass transfer over a vertical plate in the presence of magnetic field with Soret and Dufour effects, chemical reaction and a convective heat exchange at the surface with the surrounding has been studied. The similarity solution is used to transform the system of partial differential equations and an efficient numerical technique is implemented to solve the reduced system by using the Runge-Kutta fourth order method with shooting technique. The results are presented graphically and the conclusion is drawn that the flow field and other quantities of physical interest are significantly influenced by the flow parameters.